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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3BP1
All Species:
6.06
Human Site:
S277
Identified Species:
14.81
UniProt:
Q9Y3L3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3L3
NP_061830.3
701
75713
S277
F
P
R
V
Y
G
V
S
L
A
T
H
L
Q
E
Chimpanzee
Pan troglodytes
XP_515119
701
75665
S277
F
P
R
V
Y
G
V
S
L
A
T
H
L
Q
E
Rhesus Macaque
Macaca mulatta
XP_001088993
757
82612
L320
Y
A
N
Y
F
I
H
L
L
E
I
Q
A
D
Y
Dog
Lupus familis
XP_538386
703
77033
L272
Y
A
N
Y
F
I
H
L
M
E
I
Q
A
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
P55194
601
65242
D204
S
L
R
T
H
L
Q
D
L
G
R
D
I
A
L
Rat
Rattus norvegicus
Q99N37
858
93735
L258
G
T
P
L
E
E
H
L
K
R
S
G
R
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521066
476
51957
P79
S
L
Q
K
P
P
A
P
V
L
P
L
E
G
A
Chicken
Gallus gallus
XP_428489
626
68021
S229
Q
S
L
E
S
L
D
S
A
L
T
E
L
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108378
535
59728
Q138
D
I
P
N
I
Q
K
Q
R
R
H
L
A
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDS5
740
83067
R262
E
H
L
T
S
T
N
R
E
I
S
Y
I
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
75.1
74.8
N.A.
70.6
37.6
N.A.
30.2
59.2
N.A.
38.6
N.A.
26.3
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
78.1
79.2
N.A.
76.4
52.3
N.A.
40
71.6
N.A.
54.4
N.A.
44.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
0
N.A.
13.3
0
N.A.
0
26.6
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
20
N.A.
26.6
20
N.A.
13.3
33.3
N.A.
6.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
0
10
0
10
20
0
0
30
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
10
0
0
0
10
0
20
0
% D
% Glu:
10
0
0
10
10
10
0
0
10
20
0
10
10
10
40
% E
% Phe:
20
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
20
0
0
0
10
0
10
0
10
0
% G
% His:
0
10
0
0
10
0
30
0
0
0
10
20
0
0
0
% H
% Ile:
0
10
0
0
10
20
0
0
0
10
20
0
20
0
10
% I
% Lys:
0
0
0
10
0
0
10
0
10
0
0
0
0
20
0
% K
% Leu:
0
20
20
10
0
20
0
30
40
20
0
20
30
0
20
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
20
10
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
20
20
0
10
10
0
10
0
0
10
0
0
0
0
% P
% Gln:
10
0
10
0
0
10
10
10
0
0
0
20
0
20
0
% Q
% Arg:
0
0
30
0
0
0
0
10
10
20
10
0
10
0
0
% R
% Ser:
20
10
0
0
20
0
0
30
0
0
20
0
0
0
0
% S
% Thr:
0
10
0
20
0
10
0
0
0
0
30
0
0
0
0
% T
% Val:
0
0
0
20
0
0
20
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
0
0
20
20
0
0
0
0
0
0
10
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _